Masahiro Kobayashi Selected Research

Antiviral Agents (Antivirals)

1/2021	A blood-based prognostic liver secretome signature and long-term hepatocellular carcinoma risk in advanced liver fibrosis.
4/2020	Advantage of liver stiffness measurement before and after direct-acting antiviral therapy to predict hepatocellular carcinoma and exacerbation of esophageal varices in chronic hepatitis C.
12/2019	Long-term outcome of hepatocellular carcinoma occurrence, esophageal varices exacerbation, and mortality in hepatitis C virus-related liver cirrhosis after interferon-based therapy.
10/2019	Initial- and re-treatment effectiveness of glecaprevir and pibrentasvir for Japanese patients with chronic hepatitis C virus-genotype 1/2/3 infections.
2/2019	Long-term outcome of entecavir treatment of nucleos(t)ide analogue-naïve chronic hepatitis B patients in Japan.
9/2018	A Patient with HCV Infection and a Sustained Virological Response to Direct-acting Antiviral Treatment Who Developed Inclusion Body Myositis.
1/2018	Serial changes in liver stiffness and controlled attenuation parameter following direct-acting antiviral therapy against hepatitis C virus genotype 1b.
1/2018	Amino acid substitutions in the hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by all-oral direct-acting antiviral regimens.
10/2017	Direct-Acting Antivirals Decreased Tumor Recurrence After Initial Treatment of Hepatitis C Virus-Related Hepatocellular Carcinoma.
1/2017	Sustained virologic response by direct antiviral agents reduces the incidence of hepatocellular carcinoma in patients with HCV infection.

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Masahiro Kobayashi Research Topics

Disease

95	Hepatocellular Carcinoma (Hepatoma) 09/2023 - 01/2002
54	Infections 01/2021 - 01/2002
49	Chronic Hepatitis C 12/2020 - 01/2002
48	Chronic Hepatitis B 02/2022 - 01/2002
45	Fibrosis (Cirrhosis) 09/2023 - 01/2002
34	Neoplasms (Cancer) 04/2022 - 01/2002
29	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2002
26	Hepatitis 01/2014 - 01/2002
20	Liver Diseases (Liver Disease) 10/2022 - 01/2002
17	Chronic Hepatitis (Chronic Active Hepatitis) 03/2014 - 01/2003
15	Hepatitis B 01/2022 - 01/2002
15	Non-alcoholic Fatty Liver Disease 01/2022 - 01/2011
11	Type 2 Diabetes Mellitus (MODY) 04/2024 - 03/2009
11	Carcinogenesis 01/2014 - 01/2003
10	Hepatitis C 03/2016 - 09/2005
9	Anemia 01/2023 - 07/2004
8	Liver Neoplasms (Liver Cancer) 04/2022 - 12/2010
8	Diabetes Mellitus 01/2022 - 11/2008
7	Body Weight (Weight, Body) 09/2023 - 10/2007
5	Lymphoma (Lymphomas) 12/2019 - 04/2003
5	Viremia 01/2017 - 01/2007
4	Thrombocytopenia (Thrombopenia) 01/2023 - 05/2009
4	Inflammation (Inflammations) 04/2022 - 01/2003
4	Virus Diseases (Viral Diseases) 04/2021 - 01/2004
4	Neoplasm Metastasis (Metastasis) 10/2018 - 04/2002
4	Hypertension (High Blood Pressure) 03/2014 - 09/2009
4	Disease Progression 01/2014 - 01/2004
3	Fatty Liver 04/2022 - 09/2009
3	Insulin Resistance 01/2022 - 06/2009
3	Wounds and Injuries (Trauma) 01/2021 - 07/2004
3	Hepatic Encephalopathy 12/2019 - 10/2004
3	Persistent Infection 10/2013 - 05/2005
3	Liver Failure 09/2012 - 01/2004
2	Cholangitis 03/2024 - 02/2024
2	Chemical and Drug Induced Liver Injury 11/2023 - 10/2022

Drug/Important Bio-Agent (IBA)

66	InterferonsIBA 12/2020 - 01/2002
34	Lamivudine (Epivir)FDA Link 05/2017 - 01/2002
32	Ribavirin (Virazole)FDA LinkGeneric 01/2018 - 01/2002
27	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2004
27	RNA (Ribonucleic Acid)IBA 01/2019 - 01/2003
24	DNA (Deoxyribonucleic Acid)IBA 04/2022 - 02/2002
23	Hepatitis B e AntigensIBA 03/2014 - 01/2002
16	lenvatinibIBA 04/2022 - 11/2018
16	Hepatitis B Surface Antigens (HBsAg)FDA Link 01/2022 - 01/2002
15	Alanine Transaminase (SGPT)IBA 03/2016 - 01/2003
11	entecavir FDA Link 01/2022 - 06/2007
10	AntigensIBA 01/2022 - 01/2002
9	alpha-Fetoproteins (alpha-Fetoprotein)IBA 02/2020 - 01/2003
9	Amino Acids FDA Link 09/2015 - 08/2008
8	BilirubinIBA 10/2017 - 01/2003
7	miriplatinIBA 06/2017 - 01/2011
7	Transaminases (Aminotransferases)IBA 03/2012 - 08/2004
6	Biomarkers (Surrogate Marker)IBA 04/2022 - 12/2007
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022 - 08/2008
6	AlbuminsIBA 01/2019 - 01/2009
6	Serum AlbuminIBA 10/2017 - 10/2007
6	telaprevirIBA 10/2014 - 01/2010
6	adefovir dipivoxil (Hepsera)FDA Link 06/2014 - 01/2004
6	Interferon-alpha (Interferon Alfa)IBA 05/2014 - 02/2002
6	Interferon-betaIBA 01/2011 - 01/2008
5	Fetal Proteins (Fetoprotein)IBA 04/2021 - 09/2013
5	lipoarabinomannan (LAM)IBA 05/2017 - 06/2008
5	daclatasvirIBA 01/2017 - 05/2014
5	asunaprevirIBA 01/2017 - 05/2014
5	adefovirIBA 06/2014 - 01/2004
5	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2011 - 01/2006
4	NucleotidesIBA 02/2022 - 09/2004
4	Sodium-Glucose Transport ProteinsIBA 01/2022 - 01/2017
4	Sorafenib (BAY 43-9006)FDA Link 02/2021 - 06/2019
4	CreatinineIBA 08/2017 - 03/2013
4	Protease Inhibitors (Protease Inhibitor)IBA 01/2017 - 01/2010
4	Dihydrotachysterol (AT 10)IBA 01/2014 - 03/2009
4	Aspartic Acid (Aspartate)FDA Link 04/2010 - 05/2004
4	Proteins (Proteins, Gene)FDA Link 01/2010 - 03/2006
3	Prednisolone (Predate)FDA LinkGeneric 01/2024 - 10/2022
3	SodiumIBA 09/2023 - 11/2015
3	Hemoglobins (Hemoglobin)IBA 01/2023 - 11/2004
3	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2022 - 02/2002
3	Cell-Free Nucleic AcidsIBA 04/2022 - 12/2020
3	Surface Antigens (Surface Antigen)IBA 01/2022 - 12/2002
3	CanagliflozinIBA 01/2022 - 05/2019
3	TransferasesIBA 04/2021 - 08/2004
3	Tenofovir (Viread)FDA Link 04/2021 - 01/2014
3	Glucose (Dextrose)FDA LinkGeneric 02/2020 - 06/2012
3	SofosbuvirIBA 01/2018 - 01/2017
3	NucleosidesIBA 05/2017 - 06/2007
3	PlatinumIBA 03/2013 - 04/2009
3	Tyrosine (L-Tyrosine)FDA Link 04/2010 - 05/2004
3	Methionine (L-Methionine)FDA Link 04/2010 - 05/2004
2	SuspensionsIBA 01/2024 - 03/2012
2	Tolvaptan FDA Link 09/2023 - 11/2015
2	Vasopressin Receptors (Arginine Vasopressin Receptor)IBA 09/2023 - 11/2015

Therapy/Procedure

140	Therapeutics 03/2024 - 01/2002
17	Radiofrequency Ablation 02/2019 - 01/2002
8	Drug Therapy (Chemotherapy) 01/2021 - 02/2006
6	Aftercare (After-Treatment) 01/2022 - 12/2006
5	Retreatment 03/2019 - 04/2003
5	Drug Tapering 10/2013 - 07/2004
4	Hepatectomy 09/2023 - 11/2017
3	Electrodes (Electrode) 02/2019 - 01/2016